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Effect of sodium bicarbonate supplementation on the renin-angiotensin system in patients with chronic kidney disease and acidosis: a randomized clinical trial

BACKGROUND: Acidosis-induced kidney injury is mediated by the intrarenal renin-angiotensin system, for which urinary renin is a potential marker. Therefore, we hypothesized that sodium bicarbonate supplementation reduces urinary renin excretion in patients with chronic kidney disease (CKD) and metab...

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Detalles Bibliográficos
Autores principales:	Bovée, Dominique M., Roksnoer, Lodi C. W., van Kooten, Cornelis, Rotmans, Joris I., Vogt, Liffert, de Borst, Martin H., Zietse, Robert, Danser, A. H. Jan, Hoorn, Ewout J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494695/ https://www.ncbi.nlm.nih.gov/pubmed/33382448 http://dx.doi.org/10.1007/s40620-020-00944-5

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