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Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives

In this study, a novel mesoporous nanocomposite was fabricated in several steps. In this regard, SBA-15 was prepared by the hydrothermal method, next it was magnetized by in-situ preparation of Fe(3)O(4) MNPs. After that, the as-prepared SBA-15/Fe(3)O(4) functionalized with 3-minopropyltriethoxysila...

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Autores principales: Hassanzadeh-Afruzi, Fereshte, Asgharnasl, Somayeh, Mehraeen, Sara, Amiri-Khamakani, Zeinab, Maleki, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494731/
https://www.ncbi.nlm.nih.gov/pubmed/34615925
http://dx.doi.org/10.1038/s41598-021-99120-3
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author Hassanzadeh-Afruzi, Fereshte
Asgharnasl, Somayeh
Mehraeen, Sara
Amiri-Khamakani, Zeinab
Maleki, Ali
author_facet Hassanzadeh-Afruzi, Fereshte
Asgharnasl, Somayeh
Mehraeen, Sara
Amiri-Khamakani, Zeinab
Maleki, Ali
author_sort Hassanzadeh-Afruzi, Fereshte
collection PubMed
description In this study, a novel mesoporous nanocomposite was fabricated in several steps. In this regard, SBA-15 was prepared by the hydrothermal method, next it was magnetized by in-situ preparation of Fe(3)O(4) MNPs. After that, the as-prepared SBA-15/Fe(3)O(4) functionalized with 3-minopropyltriethoxysilane (APTES) via post-synthesis approach. Then, the guanidinylated SBA-15/Fe(3)O(4) was obtained by nucleophilic addition of APTES@SBA-15/Fe(3)O(4) to cyanimide. The prepared nanocomposite exhibited excellent catalytic activity in the synthesis of dihydropyrano[2,3-c]pyrazole derivatives which can be related to its physicochemical features such as strong basic sites (presented in guanidine group), Lewis acid site (presented in Fe(3)O(4)), high porous structure, and high surface area. The characterization of the prepared mesoporous nanocomposite was well accomplished by different techniques such as FT-IR, EDX, FESEM, TEM, VSM, TGA, XRD and BET. Furthermore, the magnetic catalyst was reused at least six consequent runs without considerable reduction in its catalytic activity.
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spelling pubmed-84947312021-10-07 Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives Hassanzadeh-Afruzi, Fereshte Asgharnasl, Somayeh Mehraeen, Sara Amiri-Khamakani, Zeinab Maleki, Ali Sci Rep Article In this study, a novel mesoporous nanocomposite was fabricated in several steps. In this regard, SBA-15 was prepared by the hydrothermal method, next it was magnetized by in-situ preparation of Fe(3)O(4) MNPs. After that, the as-prepared SBA-15/Fe(3)O(4) functionalized with 3-minopropyltriethoxysilane (APTES) via post-synthesis approach. Then, the guanidinylated SBA-15/Fe(3)O(4) was obtained by nucleophilic addition of APTES@SBA-15/Fe(3)O(4) to cyanimide. The prepared nanocomposite exhibited excellent catalytic activity in the synthesis of dihydropyrano[2,3-c]pyrazole derivatives which can be related to its physicochemical features such as strong basic sites (presented in guanidine group), Lewis acid site (presented in Fe(3)O(4)), high porous structure, and high surface area. The characterization of the prepared mesoporous nanocomposite was well accomplished by different techniques such as FT-IR, EDX, FESEM, TEM, VSM, TGA, XRD and BET. Furthermore, the magnetic catalyst was reused at least six consequent runs without considerable reduction in its catalytic activity. Nature Publishing Group UK 2021-10-06 /pmc/articles/PMC8494731/ /pubmed/34615925 http://dx.doi.org/10.1038/s41598-021-99120-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hassanzadeh-Afruzi, Fereshte
Asgharnasl, Somayeh
Mehraeen, Sara
Amiri-Khamakani, Zeinab
Maleki, Ali
Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
title Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
title_full Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
title_fullStr Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
title_full_unstemmed Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
title_short Guanidinylated SBA-15/Fe(3)O(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
title_sort guanidinylated sba-15/fe(3)o(4) mesoporous nanocomposite as an efficient catalyst for the synthesis of pyranopyrazole derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494731/
https://www.ncbi.nlm.nih.gov/pubmed/34615925
http://dx.doi.org/10.1038/s41598-021-99120-3
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