ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation

Sphingolipid metabolic dysregulation has increasingly been considered to be a drug-resistance mechanism for a variety of tumors. In this study, through an LC–MS assay, LIM and SH3 protein 1 (LASP1) was identified as a sphingolipid-metabolism-involved protein, and short-chain enoyl-CoA hydratase (ECH...

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Detalles Bibliográficos
Autores principales: Li, Rui, Hao, Yanyu, Wang, Qiuhan, Meng, Yuan, Wu, Kunhe, Liu, Chaoqun, Xu, Lijun, Liu, Ziguang, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494735/
https://www.ncbi.nlm.nih.gov/pubmed/34615856
http://dx.doi.org/10.1038/s41419-021-04213-6

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