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The SARM1 TIR NADase: Mechanistic Similarities to Bacterial Phage Defense and Toxin-Antitoxin Systems

The Toll/interleukin-1 receptor (TIR) domain is the signature signalling motif of innate immunity, with essential roles in innate immune signalling in bacteria, plants, and animals. TIR domains canonically function as scaffolds, with stimulus-dependent multimerization generating binding sites for si...

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Detalles Bibliográficos
Autores principales:	DiAntonio, Aaron, Milbrandt, Jeffrey, Figley, Matthew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494770/ https://www.ncbi.nlm.nih.gov/pubmed/34630431 http://dx.doi.org/10.3389/fimmu.2021.752898

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