Cargando…

CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease

Phenotypic definition of helper ILC1 and NK cells is problematic due to overlapping markers. Recently we showed the identification of cytotoxic ILC3s characterized by expression of CD94. Here we analyse CD127+ ILCs and NK cells in intestinal lamina propria from healthy donors and Crohn’s disease pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krabbendam, L., Heesters, B. A., Kradolfer, C. M. A., Haverkate, N. J. E., Becker, M. A. J., Buskens, C. J., Bemelman, W. A., Bernink, J. H., Spits, H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494908/ https://www.ncbi.nlm.nih.gov/pubmed/34615883 http://dx.doi.org/10.1038/s41467-021-26187-x

Ejemplares similares

Identification of human cytotoxic ILC3s
por: Krabbendam, Lisette, et al.
Publicado: (2021)

Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells
por: Walch, Michael, et al.
Publicado: (2007)

KLRG1 and NKp46 discriminate subpopulations of human CD117(+)CRTH2(−) ILCs biased toward ILC2 or ILC3
por: Nagasawa, Maho, et al.
Publicado: (2019)

Correction: KLRG1 and NKp46 discriminate subpopulations of human CD117(+)CRTH2(−) ILCs biased toward ILC2 or ILC3
por: Nagasawa, Maho, et al.
Publicado: (2019)

Induction of Granulysin and Perforin Cytolytic Mediator Expression in 10-Week-Old Infants Vaccinated with BCG at Birth
por: Semple, Patricia L., et al.
Publicado: (2011)

Role of human innate lymphoid cells in IMID
por: Spits, Hergen, et al.
Publicado: (2012)

Use of the Human Granulysin Transgenic Mice To Evaluate the Role of Granulysin Expression by CD8 T Cells in Immunity To Mycobacterium tuberculosis
por: Thakur, Preeti, et al.
Publicado: (2022)

GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation
por: van Lier, Y. F., et al.
Publicado: (2022)

A Profound Membrane Reorganization Defines Susceptibility of Plasmodium falciparum Infected Red Blood Cells to Lysis by Granulysin and Perforin
por: Hernández-Castañeda, Maria Andrea, et al.
Publicado: (2021)

Granulysin-Expressing CD4(+) T Cells as Candidate Immune Marker for Tuberculosis during Childhood and Adolescence
por: Mueller, Henrik, et al.
Publicado: (2011)

Transcriptome analysis reveals similarities between human blood CD3(−) CD56(bright) cells and mouse CD127(+) innate lymphoid cells
por: Allan, David S. J., et al.
Publicado: (2017)

Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens
por: Fergusson, Joannah R., et al.
Publicado: (2019)

Granulysin expression and granulysin-mediated apoptosis in the peripheral blood of osteoarthritis patients
por: Drvar, Vedrana, et al.
Publicado: (2022)

Progressive Activation of CD127+132− Recent Thymic Emigrants into Terminally Differentiated CD127−132+ T-Cells in HIV-1 Infection
por: Sasson, Sarah C., et al.
Publicado: (2012)

FcαRI co-stimulation converts human intestinal CD103(+) dendritic cells into pro-inflammatory cells through glycolytic reprogramming
por: Hansen, Ivo S., et al.
Publicado: (2018)

Human CD5(+) Innate Lymphoid Cells Are Functionally Immature and Their Development from CD34(+) Progenitor Cells Is Regulated by Id2
por: Nagasawa, Maho, et al.
Publicado: (2017)

Decreased CD127 Expression on CD4+ T-Cells and Elevated Frequencies of CD4+CD25+CD127− T-Cells in Children with Long-Lasting Type 1 Diabetes
por: Moniuszko, Marcin, et al.
Publicado: (2013)

Coordinated In Vitro Release of Granulysin, Perforin and IFN-γ in TB and HIV/TB Co-Infection Associated with Clinical Outcomes before and after Anti-TB Treatment
por: Pitabut, Nada, et al.
Publicado: (2020)

IL-2 receptor γ chain cytokines differentially regulate human CD8(+)CD127(+) and CD8(+)CD127(−) T cell division and susceptibility to apoptosis
por: Crawley, Angela M., et al.
Publicado: (2009)

Single‐cell profiling of human CD127(+) innate lymphoid cells reveals diverse immune phenotypes in hepatocellular carcinoma
por: He, Yuanlin, et al.
Publicado: (2022)

Perforin Competent CD8 T Cells Are Sufficient to Cause Immune-Mediated Blood-Brain Barrier Disruption
por: Johnson, Holly L., et al.
Publicado: (2014)

Human ILC1: To Be or Not to Be
por: Bernink, Jochem H., et al.
Publicado: (2017)

Increased frequency of CD4(+)CD25(high) CD127(low/)(−) regulatory T cells in patients with multiple sclerosis
por: Khosravi, Maryam, et al.
Publicado: (2019)

Development and Function of CD94-Deficient Natural Killer Cells
por: Orr, Mark T., et al.
Publicado: (2010)

The major CD8 T cell effector memory subset in the normal and Chlamydia trachomatis-infected human endocervix is low in perforin
por: Ibana, Joyce A, et al.
Publicado: (2012)

Tag7 (PGLYRP1) Can Induce an Emergence of the CD3+CD4+CD25+CD127+ Cells with Antitumor Activity
por: Sharapova, T. N., et al.
Publicado: (2018)

CD4(+)CD25(high)CD127(-) regulatory T-cells in COPD: smoke and drugs effect
por: Chiappori, Alessandra, et al.
Publicado: (2016)

Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation
Publicado: (1996)

Increased CD127+ and decreased CD57+ T cell expression levels in HIV-infected patients on NRTI-sparing regimens
por: Gonzalez-Serna, A., et al.
Publicado: (2017)

CD4(+)CD25(+)CD127(hi) cell frequency predicts disease progression in type 1 diabetes
por: Narsale, Aditi, et al.
Publicado: (2021)

Comparative Antimicrobial Activity of Granulysin against Bacterial Biothreat Agents
por: Endsley, Janice J, et al.
Publicado: (2009)

Collisional variant of CD8(+) mycosis fungoides and indolent CD8(+) lymphoid proliferation
por: Lopez, Adriana, et al.
Publicado: (2020)

IL‐7 induces sCD127 release and mCD127 downregulation in human CD8(+) T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection
por: Côté, Sandra C., et al.
Publicado: (2020)

Cytotoxicity of CD19-CAR-NK92 cells is primarily mediated via perforin/granzyme pathway
por: Althaus, Jonas, et al.
Publicado: (2023)

Detection and Significance of CD4+CD25+CD127dim Regulatory T Cells in Individuals with Severe Aplastic Anemia
por: Qi, Weiwei, et al.
Publicado: (2015)

Peripheral CD4(+)CD25(hi)CD127(low) regulatory T cells are increased in patients with gastrointestinal cancer
por: Qiu, Junlan, et al.
Publicado: (2023)

Systematic review and meta‐analysis of endorectal advancement flap and ligation of the intersphincteric fistula tract for cryptoglandular and Crohn's high perianal fistulas
por: Stellingwerf, M. E., et al.
Publicado: (2019)

Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4(+)CD45RO(+)CD25(+)CD127(low) regulatory T cells
por: Walter, Gina J, et al.
Publicado: (2012)

Synovial fluid CD69(+)CD8(+) T cells with tissue‐resident phenotype mediate perforin‐dependent citrullination in rheumatoid arthritis
por: Jung, Jae Hyung, et al.
Publicado: (2020)

Role of CD4(+)CD25(hi)CD127(lo/-)FoxP3(+) regulatory T lymphocytes in the pathogenesis of Behçet’s disease in children
por: Tran, TA, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ks9qdfnjinks8qg89dkh0dcfgl