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First-in-class topical therapeutic omilancor ameliorates disease severity and inflammation through activation of LANCL2 pathway in psoriasis
Psoriasis (PsO) is a complex immune-mediated disease that afflicts 100 million people. Omilancor is a locally-acting, small molecule that selectively activates the Lanthionine Synthetase C-like 2 (LANCL2) pathway, resulting in immunoregulatory effects at the intersection of immunity and metabolism....
Autores principales: | Tubau-Juni, Nuria, Hontecillas, Raquel, Leber, Andrew, Maturavongsadit, Panita, Chauhan, Jyoti, Bassaganya-Riera, Josep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494925/ https://www.ncbi.nlm.nih.gov/pubmed/34615968 http://dx.doi.org/10.1038/s41598-021-99349-y |
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