A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition

The likelihood of continued circulation of COVID-19 and its variants, and novel coronaviruses due to future zoonotic transmissions, combined with the current paucity of coronavirus antivirals, emphasize the need for improved screening in developing effective antivirals for the treatment of infection...

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Detalles Bibliográficos
Autores principales: Dey-Rao, Rama, Smith, George R., Timilsina, Uddhav, Falls, Zackary, Samudrala, Ram, Stavrou, Spyridon, Melendy, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495046/
https://www.ncbi.nlm.nih.gov/pubmed/34626674
http://dx.doi.org/10.1016/j.antiviral.2021.105183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495046/
https://www.ncbi.nlm.nih.gov/pubmed/34626674
http://dx.doi.org/10.1016/j.antiviral.2021.105183

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