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Research Progress About Glioma Stem Cells in the Immune Microenvironment of Glioma

Gliomas are the most common primary tumors of the central nervous system. Due to the existence of the blood-brain barrier and its unique regional immune characteristics, the study of the immune microenvironment of gliomas is particularly important. Glioma stem cells are an important cause of initiat...

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Detalles Bibliográficos
Autores principales: Li, Xiangyu, Liu, Ming, Zhao, Junfeng, Ren, Tong, Yan, Xin, Zhang, Lijun, Wang, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495125/
https://www.ncbi.nlm.nih.gov/pubmed/34630121
http://dx.doi.org/10.3389/fphar.2021.750857
Descripción
Sumario:Gliomas are the most common primary tumors of the central nervous system. Due to the existence of the blood-brain barrier and its unique regional immune characteristics, the study of the immune microenvironment of gliomas is particularly important. Glioma stem cells are an important cause of initiating glioma, promoting tumor progression and leading to tumor recurrence. Immunotherapeutic strategies targeting glioma stem cells have become the focus of current research. This paper will focus on the research progress of glioma stem cells in the immune microenvironment of glioma to provide the basis for the immunotherapy of glioma.