Melittin-loaded Iron Oxide Nanoparticles Prevent Intracranial Arterial Dolichoectasia Development through Inhibition of Macrophage-mediated Inflammation

Rationale: In intracranial arterial dolichoectasia (IADE) development, the feedback loop between inflammatory cytokines and macrophages involves TNF-α and NF-κB signaling pathways and leads to subsequent MMP-9 activation and extracellular matrix (ECM) degeneration. In this proof-of-concept study, me...

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Detalles Bibliográficos
Autores principales: Vu, Huy Duc, Huynh, Phuong Tu, Ryu, Junghwa, Kang, Ung Rae, Youn, Sung Won, Kim, Hongtae, Ahn, Hyun Jin, Park, Kwankyu, Hwang, Soon-Kyung, Chang, Young-Chae, Lee, Yong Jig, Lee, Hui Joong, Lee, Jongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495379/
https://www.ncbi.nlm.nih.gov/pubmed/34671201
http://dx.doi.org/10.7150/ijbs.60588

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