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Up-regulation of MELK by E2F1 promotes the proliferation in cervical cancer cells

Cervical cancer is a common gynecologic cancer and a frequent cause of death. In this study, we investigated the role of MELK (maternal embryonic leucine zipper kinase) in cervical cancer. We found that HPV 18 E6/E7 promoted MELK expression by activating E2F1. MELK knockdown blocked cancer cells gro...

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Detalles Bibliográficos
Autores principales:	Sun, Hongzhi, Ma, Hongmei, Zhang, Hao, Ji, Minjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495384/ https://www.ncbi.nlm.nih.gov/pubmed/34671205 http://dx.doi.org/10.7150/ijbs.62517

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