Cargando…

COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2

Furin is a proprotein convertase that activates different kinds of regulatory proteins, including SARS-CoV-2 spike protein which contains an additional furin-specific cleavage site. It is essential in predicting cancer patients' susceptibility to SARS-CoV-2 and the disease outcomes due to varyi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Dabing, Liu, Xiaoyan, Zhang, Lianmei, He, Jiayue, Chen, Xianmao, Liu, Shuguang, Fu, Jiewen, Fu, Shangyi, Chen, Hanchun, Fu, Junjiang, Cheng, Jingliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495395/ https://www.ncbi.nlm.nih.gov/pubmed/34671211 http://dx.doi.org/10.7150/ijbs.63072

Ejemplares similares

COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2
por: Zhang, Lianmei, et al.
Publicado: (2022)

Impact of TMPRSS2 Expression, Mutation Prognostics, and Small Molecule (CD, AD, TQ, and TQFL12) Inhibition on Pan-Cancer Tumors and Susceptibility to SARS-CoV-2
por: Fu, Jiewen, et al.
Publicado: (2022)

Prostate adenocarcinoma and COVID‐19: The possible impacts of TMPRSS2 expressions in susceptibility to SARS‐CoV‐2
por: Cheng, Jingliang, et al.
Publicado: (2021)

Impact of BSG/CD147 gene expression on diagnostic, prognostic and therapeutic strategies towards malignant cancers and possible susceptibility to SARS-CoV-2
por: Fu, Jiewen, et al.
Publicado: (2022)

The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals
por: Cheng, Jingliang, et al.
Publicado: (2022)

Effect of DPP4/CD26 expression on SARS-CoV-2 susceptibility, immune response, adenosine (derivatives m(6)(2)A and CD) regulations on patients with cancer and healthy individuals
por: Du, Jiaman, et al.
Publicado: (2023)

The Correlation Between Immune Invasion and SARS-COV-2 Entry Protein ADAM17 in Cancer Patients by Bioinformatic Analysis
por: Wang, Kai, et al.
Publicado: (2022)

Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19
por: Fu, Jiewen, et al.
Publicado: (2020)

Antiviral Potential of Small Molecules Cordycepin, Thymoquinone, and N6, N6-Dimethyladenosine Targeting SARS-CoV-2 Entry Protein ADAM17
por: He, Jiayue, et al.
Publicado: (2022)

Roles of MicroRNA-34a in Epithelial to Mesenchymal Transition, Competing Endogenous RNA Sponging and Its Therapeutic Potential
por: Nie, Dongsong, et al.
Publicado: (2019)

Impacts of transmembrane serine protease 4 expression on susceptibility to severe acute respiratory syndrome coronavirus 2
por: Tan, Qi, et al.
Publicado: (2023)

A novel missense variant c.G644A (p.G215E) of the RPGR gene in a Chinese family causes X-linked retinitis pigmentosa
por: Fu, Jiewen, et al.
Publicado: (2019)

Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China
por: Fu, Jiewen, et al.
Publicado: (2023)

A novel, homozygous nonsense variant of the CDHR1 gene in a Chinese family causes autosomal recessive retinal dystrophy by NGS‐based genetic diagnosis
por: Fu, Jiewen, et al.
Publicado: (2018)

The speckle-type POZ protein (SPOP) inhibits breast cancer malignancy by destabilizing TWIST1
por: Wei, Chunli, et al.
Publicado: (2022)

Identification of a novel germline BRCA2 variant in a Chinese breast cancer family
por: Cheng, Jingliang, et al.
Publicado: (2019)

A novel splicing mutation in the PRPH2 gene causes autosomal dominant retinitis pigmentosa in a Chinese pedigree
por: Cheng, Jingliang, et al.
Publicado: (2019)

Targeted Next-Generation Sequencing Identified Novel Compound Heterozygous Variants in the CDH23 Gene Causing Usher Syndrome Type ID in a Chinese Patient
por: Zhang, Lianmei, et al.
Publicado: (2020)

In silico data analyses of the hotspot mutations of CHM gene in choroideremia disease
por: Imani, Saber, et al.
Publicado: (2018)

A case of Usher syndrome type IIA caused by a rare USH2A homozygous frameshift variant with maternal uniparental disomy (UPD) in a Chinese family
por: Fu, Jiewen, et al.
Publicado: (2020)

TQFL12, a novel synthetic derivative of TQ, inhibits triple‐negative breast cancer metastasis and invasion through activating AMPK/ACC pathway
por: Wei, Chunli, et al.
Publicado: (2021)

Evaluation and characterization of HSPA5 (GRP78) expression profiles in normal individuals and cancer patients with COVID-19
por: Fu, Jiewen, et al.
Publicado: (2021)

Novel, heterozygous, de novo pathogenic variant (c.4963delA: p.Thr1656Glnfs*42) of the NF1 gene in a Chinese family with neurofibromatosis type 1
por: Yang, Lisha, et al.
Publicado: (2023)

Genetic polymorphism of 19 autosomal STR loci in the Yi ethnic minority of Liangshan Yi autonomous prefecture from Sichuan province in China
por: Cheng, Jingliang, et al.
Publicado: (2021)

Genetic Polymorphism and Population Genetic Structure Analysis of 21 Autosomal STR Loci for a Han-Chinese Population from Luzhou of Southwest China
por: Song, Binghui, et al.
Publicado: (2023)

Genetic Authentication of Gardenia jasminoides Ellis var. grandiflora Nakai by Improved RAPD-Derived DNA Markers
por: Mei, Zhiqiang, et al.
Publicado: (2015)

New progresses on cell surface protein HSPA5/BiP/GRP78 in cancers and COVID-19
por: Li, Ting, et al.
Publicado: (2023)

Development of diagnostic SCAR markers for genomic DNA amplifications in breast carcinoma by DNA cloning of high-GC RAMP-PCR fragments
por: Fu, Shangyi, et al.
Publicado: (2017)

SARS-CoV-2 furin cleavage site was not engineered
por: Garry, Robert F.
Publicado: (2022)

Transgenic overexpression of furin increases epileptic susceptibility
por: Yang, Yi, et al.
Publicado: (2018)

Genetic identification and molecular modeling characterization reveal a novel PROM1 mutation in Stargardt4-like macular dystrophy
por: Imani, Saber, et al.
Publicado: (2017)

Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1
por: Li, Jun, et al.
Publicado: (2017)

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis
por: Johnson, Bryan A., et al.
Publicado: (2020)

The Emergence of the Spike Furin Cleavage Site in SARS-CoV-2
por: Chan, Yujia Alina, et al.
Publicado: (2021)

Comprehensive analysis, immune, and cordycepin regulation for SOX9 expression in pan-cancers and the matched healthy tissues
por: Liu, Shuguang, et al.
Publicado: (2023)

Thymoquinone, as an anticancer molecule: from basic research to clinical investigation
por: Asaduzzaman Khan, Md., et al.
Publicado: (2017)

Novel compound heterozygous EYS variants may be associated with arRP in a large Chinese pedigree
por: Wei, Chunli, et al.
Publicado: (2020)

A novel homozygous variant of GPR98 causes usher syndrome type IIC in a consanguineous Chinese family by next generation sequencing
por: Wei, Chunli, et al.
Publicado: (2018)

Dysregulated ACE2 and Furin Activity amongst Smokers Increase Disease Susceptibility Towards SARS-CoV2
por: Kaur, Gagandeep, et al.
Publicado: (2020)

CTSL, a prognostic marker of breast cancer, that promotes proliferation, migration, and invasion in cells in triple-negative breast cancer
por: Zhang, Lianmei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k6e1gmsuuurttic0m757ld69ie