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Real-time quantification of the transmission advantage associated with a single mutation in pathogen genomes: a case study on the D614G substitution of SARS-CoV-2
BACKGROUND: The COVID-19 pandemic poses serious threats to global health, and the emerging mutation in SARS-CoV-2 genomes, e.g., the D614G substitution, is one of the major challenges of disease control. Characterizing the role of the mutation activities is of importance to understand how the evolut...
Autores principales: | Zhao, Shi, Lou, Jingzhi, Cao, Lirong, Zheng, Hong, Chong, Marc K. C., Chen, Zigui, Chan, Renee W. Y., Zee, Benny C. Y., Chan, Paul K. S., Wang, Maggie H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495436/ https://www.ncbi.nlm.nih.gov/pubmed/34620109 http://dx.doi.org/10.1186/s12879-021-06729-w |
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