Myeloid cell‐based delivery of IFN‐γ reprograms the leukemia microenvironment and induces anti‐tumoral immune responses

The immunosuppressive microenvironment surrounding tumor cells represents a key cause of treatment failure. Therefore, immunotherapies aimed at reprogramming the immune system have largely spread in the past years. We employed gene transfer into hematopoietic stem and progenitor cells to selectively...

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Detalles Bibliográficos
Autores principales: Mucci, Adele, Antonarelli, Gabriele, Caserta, Carolina, Vittoria, Francesco Maria, Desantis, Giacomo, Pagani, Riccardo, Greco, Beatrice, Casucci, Monica, Escobar, Giulia, Passerini, Laura, Lachmann, Nico, Sanvito, Francesca, Barcella, Matteo, Merelli, Ivan, Naldini, Luigi, Gentner, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495462/
https://www.ncbi.nlm.nih.gov/pubmed/34459560
http://dx.doi.org/10.15252/emmm.202013598

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