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Neurofilament Light in CSF and Plasma Is a Marker of Neuronal Damage in HTLV-1–Associated Myelopathy and Correlates With Neuroinflammation

BACKGROUND AND OBJECTIVES: To evaluate the usefulness of CSF and plasma neurofilament light (Nf-L) as a biomarker for human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM). METHODS: Nf-L, CXCL10, and neopterin were measured by ELISA in 83 CSF samples obtained from 49 individual...

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Detalles Bibliográficos
Autores principales: Rosadas, Carolina, Zetterberg, Henrik, Heslegrave, Amanda, Haddow, Jana, Borisova, Mina, Taylor, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495502/
https://www.ncbi.nlm.nih.gov/pubmed/34611039
http://dx.doi.org/10.1212/NXI.0000000000001090