Cargando…

Neurofilament Light in CSF and Plasma Is a Marker of Neuronal Damage in HTLV-1–Associated Myelopathy and Correlates With Neuroinflammation

BACKGROUND AND OBJECTIVES: To evaluate the usefulness of CSF and plasma neurofilament light (Nf-L) as a biomarker for human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM). METHODS: Nf-L, CXCL10, and neopterin were measured by ELISA in 83 CSF samples obtained from 49 individual...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rosadas, Carolina, Zetterberg, Henrik, Heslegrave, Amanda, Haddow, Jana, Borisova, Mina, Taylor, Graham P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495502/ https://www.ncbi.nlm.nih.gov/pubmed/34611039 http://dx.doi.org/10.1212/NXI.0000000000001090

Ejemplares similares

Refining the risk of HTLV-1-associated myelopathy in people living with HTLV-1: identification of a HAM-like phenotype in a proportion of asymptomatic carriers
por: Harding, Daniel, et al.
Publicado: (2022)

Anti-HTLV-1/2 IgG Antibodies in the Breastmilk of Seropositive Mothers
por: Rosadas, Carolina, et al.
Publicado: (2021)

Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome
por: Strydom, Andre, et al.
Publicado: (2018)

Cerebrospinal fluid neurofilament light chain levels in CLN2 disease patients treated with enzyme replacement therapy normalise after two years on treatment
por: Iwan, Katharina, et al.
Publicado: (2022)

Effect of Pulsed Methylprednisolone on Pain, in Patients with HTLV-1-Associated Myelopathy
por: Buell, Kevin G., et al.
Publicado: (2016)

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures
por: Mielke, Michelle M., et al.
Publicado: (2019)

Neurofilament light predicts neurological outcome after subarachnoid haemorrhage
por: Garland, Patrick, et al.
Publicado: (2021)

CSF neurofilament light concentration is increased in presymptomatic CHMP2B mutation carriers
por: Rostgaard, Nina, et al.
Publicado: (2018)

Treatment of patients with HTLV-1-associated myelopathy with methotrexate
por: Ahmed, S, et al.
Publicado: (2014)

HTLV-1 and Co-infections
por: Rosadas, Carolina, et al.
Publicado: (2022)

Neurofilament light in CSF and serum is a sensitive marker for axonal white matter injury in MS
por: Bergman, Joakim, et al.
Publicado: (2016)

Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression
por: Thompson, Andrew Geoffrey Bourne, et al.
Publicado: (2018)

CSF Neurofilament light chain level predicts axonal damage in cerebral vasculitis
por: Pawlitzki, Marc, et al.
Publicado: (2019)

Neurofilament light chain: defining the analyte
por: Leckey, Claire A., et al.
Publicado: (2022)

Exploring CSF neurofilament light as a biomarker for MS in clinical practice; a retrospective registry-based study
por: Rosenstein, Igal, et al.
Publicado: (2021)

Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease
por: Sánchez-Valle, Raquel, et al.
Publicado: (2018)

Association of plasma neurofilament light chain with disease activity in chronic inflammatory demyelinating polyradiculoneuropathy
por: Kapoor, Mahima, et al.
Publicado: (2022)

Correlation between CSF and blood neurofilament light chain protein: a systematic review and meta-analysis
por: Alagaratnam, Jasmini, et al.
Publicado: (2021)

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease
por: Weston, Philip S. J., et al.
Publicado: (2019)

The prognostic significance of early blood neurofilament light chain concentration and magnetic resonance imaging variables in relapse‐onset multiple sclerosis
por: Williams, Thomas, et al.
Publicado: (2022)

Plasma p-tau181, neurofilament light chain and association with cognition in Parkinson’s disease
por: Batzu, Lucia, et al.
Publicado: (2022)

Mother-to-Child HTLV-1 Transmission: Unmet Research Needs
por: Rosadas, Carolina, et al.
Publicado: (2019)

Is CSF neurofilament light chain measurement relevant for MS?
por: Matsui, Makoto
Publicado: (2020)

Neurofilament light protein in CSF and blood is associated with neurodegeneration and disease severity in Huntington’s disease R6/2 mice
por: Soylu-Kucharz, Rana, et al.
Publicado: (2017)

Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients
por: Page, Valerie J, et al.
Publicado: (2022)

Increased CSF Levels of Phosphorylated Neurofilament Heavy Protein following Bout in Amateur Boxers
por: Neselius, Sanna, et al.
Publicado: (2013)

No evidence of neuronal damage as measured by neurofilament light chain in a HIV cure study utilising a kick-and-kill approach
por: Alagaratnam, Jasmini, et al.
Publicado: (2021)

Increased serum neurofilament light chain concentration indicates poor outcome in Guillain-Barré syndrome
por: Altmann, Patrick, et al.
Publicado: (2020)

Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease
por: Steinacker, Petra, et al.
Publicado: (2016)

Following the Clues: Usefulness of Biomarkers of Neuroinflammation and Neurodegeneration in the Investigation of HTLV-1-Associated Myelopathy Progression
por: Souza, Flávia dos Santos, et al.
Publicado: (2021)

The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias
por: Abu-Rumeileh, Samir, et al.
Publicado: (2018)

Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy
por: Weinhofer, Isabelle, et al.
Publicado: (2021)

Neurofilament light in blood – What more is needed for clinical implementation in multiple sclerosis?
por: Zetterberg, Henrik
Publicado: (2020)

Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial
por: Williams, Thomas, et al.
Publicado: (2022)

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers
por: Ashton, Nicholas J., et al.
Publicado: (2019)

HTLV-1 as a contributing factor towards scabies and its systemic sequelae
por: Cockbain, Beatrice, et al.
Publicado: (2023)

Plasma Neurofilament Light as a Biomarker of Neurological Involvement in Wilson's Disease
por: Shribman, Samuel, et al.
Publicado: (2020)

Correlation between cerebrospinal fluid and plasma neurofilament light protein in treated HIV infection: results from the COBRA study
por: Alagaratnam, Jasmini, et al.
Publicado: (2021)

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease
por: Mattsson, Niklas, et al.
Publicado: (2017)

Current Interventions to Prevent HTLV-1 Mother-to-Child Transmission and Their Effectiveness: A Systematic Review and Meta-Analysis
por: Rosadas, Carolina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vt0nfv64vm5kci4fiqaes744c3