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Experimental exchange of paralogous domains in the MLH family provides evidence of sub-functionalization after gene duplication

Baker’s yeast contains a large number of duplicated genes; some function redundantly, whereas others have more specialized roles. We used the MLH family of DNA mismatch repair (MMR) proteins as a model to better understand the steps that lead to gene specialization following a gene duplication event...

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Detalles Bibliográficos
Autores principales:	Furman, Christopher M, Elbashir, Ryan, Pannafino, Gianno, Clark, Nathan L, Alani, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495741/ https://www.ncbi.nlm.nih.gov/pubmed/33871573 http://dx.doi.org/10.1093/g3journal/jkab111

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