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Estimating the effective sample size in association studies of quantitative traits

The effective sample size (ESS) is a metric used to summarize in a single term the amount of correlation in a sample. It is of particular interest when predicting the statistical power of genome-wide association studies (GWAS) based on linear mixed models. Here, we introduce an analytical form of th...

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Detalles Bibliográficos
Autores principales: Ziyatdinov, Andrey, Kim, Jihye, Prokopenko, Dmitry, Privé, Florian, Laporte, Fabien, Loh, Po-Ru, Kraft, Peter, Aschard, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495748/
https://www.ncbi.nlm.nih.gov/pubmed/33734375
http://dx.doi.org/10.1093/g3journal/jkab057