Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in Drosophila

Advanced age in humans is associated with greater susceptibility to and higher mortality rates from infections, including infections with some RNA viruses. The underlying innate immune mechanisms, which represent the first line of defense against pathogens, remain incompletely understood. Drosophila...

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Detalles Bibliográficos
Autores principales: Sheffield, Lakbira, Sciambra, Noah, Evans, Alysa, Hagedorn, Eli, Goltz, Casey, Delfeld, Megan, Kuhns, Haley, Fierst, Janna L, Chtarbanova, Stanislava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495950/
https://www.ncbi.nlm.nih.gov/pubmed/33836060
http://dx.doi.org/10.1093/g3journal/jkab116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495950/
https://www.ncbi.nlm.nih.gov/pubmed/33836060
http://dx.doi.org/10.1093/g3journal/jkab116

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