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Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in Drosophila
Advanced age in humans is associated with greater susceptibility to and higher mortality rates from infections, including infections with some RNA viruses. The underlying innate immune mechanisms, which represent the first line of defense against pathogens, remain incompletely understood. Drosophila...
Autores principales: | Sheffield, Lakbira, Sciambra, Noah, Evans, Alysa, Hagedorn, Eli, Goltz, Casey, Delfeld, Megan, Kuhns, Haley, Fierst, Janna L, Chtarbanova, Stanislava |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495950/ https://www.ncbi.nlm.nih.gov/pubmed/33836060 http://dx.doi.org/10.1093/g3journal/jkab116 |
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