Cargando…

Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer

OBJECTIVE: Epithelial ovarian cancer (EOC) is a heterogeneous disease with diverse clinicopathological features and behaviors, and its heterogeneity may be concerned with the accumulation of multiple somatic oncogenic mutations. The major goals of this study are to systematically perform the compreh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Takafumi, Nanamiya, Hideaki, Endo, Yuta, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tamura, Hirosumi, Ryufuku, Masae, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-ichi, Watanabe, Shinya, Fujimori, Keiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496016/ https://www.ncbi.nlm.nih.gov/pubmed/34615547 http://dx.doi.org/10.1186/s13048-021-00876-z

Ejemplares similares

Clinical implication of oncogenic somatic mutations in early-stage cervical cancer with radical hysterectomy
por: Watanabe, Takafumi, et al.
Publicado: (2020)

Clinical relevance of oncogenic driver mutations identified in endometrial carcinoma
por: Watanabe, Takafumi, et al.
Publicado: (2021)

Prediction of lymphovascular space invasion in endometrial cancer using the 55-gene signature selected by DNA microarray analysis
por: Watanabe, Takafumi, et al.
Publicado: (2019)

Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues
por: Tamura, Hirosumi, et al.
Publicado: (2018)

The measurement of stiffness of uterine smooth muscle tumor by elastography
por: Furukawa, Shigenori, et al.
Publicado: (2014)

Reduced Claudin-12 Expression Predicts Poor Prognosis in Cervical Cancer
por: Rahman, Abidur, et al.
Publicado: (2021)

Sclerosing stromal tumor of the ovary treated with 2-incision total laparoscopic cystectomy
por: Furukawa, Shigenori, et al.
Publicado: (2015)

Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer
por: Kojima, Manabu, et al.
Publicado: (2020)

Addendum: Manabu, K., et al. Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer. Cancers 2020, 12, 2748
por: Kojima, Manabu, et al.
Publicado: (2021)

Rare Hereditary Gynecological Cancer Syndromes
por: Watanabe, Takafumi, et al.
Publicado: (2022)

Successful laparoscopic resection of ovarian abscess caused by Staphylococcus aureus in a 13-year-old girl: a case report and review of literature
por: Murata, Tsuyoshi, et al.
Publicado: (2021)

Successful management of pelvic recurrence of MSI-High endometrial cancer by total pelvic exenteration followed by administration of pembrolizumab: A case report
por: Kojima, Manabu, et al.
Publicado: (2022)

Claudin-9 is a novel prognostic biomarker for endometrial cancer
por: Endo, Yuta, et al.
Publicado: (2022)

SPON1 is an independent prognostic biomarker for ovarian cancer
por: Miyakawa, Ryoya, et al.
Publicado: (2023)

Serum levels of rapid turnover proteins are decreased and related to systemic inflammation in patients with ovarian cancer
por: WATANABE, TAKAFUMI, et al.
Publicado: (2014)

Malignant transformation arising from mature cystic teratoma of the ovary presenting as ovarian torsion: a case report and literature review
por: Toba, Naoya, et al.
Publicado: (2020)

A rare case of recurrent ovarian cancer with TPM3-NTRK1 gene rearrangement: A case report
por: Endo, Yuta, et al.
Publicado: (2022)

Mild phenotypes associated with an unbalanced X‐autosome translocation, 46,X,der(X)t(X;8)(q28;q13)
por: Watanabe, Takafumi, et al.
Publicado: (2018)

Successful Planned Pregnancy through Vitrified-Warmed Embryo Transfer in a Woman with Chronic Myeloid Leukemia: Case Report and Literature Review
por: Furukawa, Yuka, et al.
Publicado: (2020)

Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination
por: Watanabe, Takafumi, et al.
Publicado: (2012)

Successful pregnancy and term delivery after treatment of unicornuate uterus with non-communicating rudimentary horn pregnancy with local methotrexate injection followed by laparoscopic resection: a case report and literature review
por: Ueda, Makiko, et al.
Publicado: (2021)

Synchronous bilateral primary ovarian cancer with right endometroid carcinoma and left high-grade serous carcinoma: a case report and literature review
por: Fujimori, Mimori, et al.
Publicado: (2022)

Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden
por: Muto, Satoshi, et al.
Publicado: (2021)

Successful pregnancy and delivery after a vitrified-warmed embryo transfer in a woman with Kallmann syndrome: A case report and literature review
por: Shiraiwa, Aya, et al.
Publicado: (2022)

Polyhydramnios and abnormal foetal heart rate patterns in a foetus with Prader-Willi syndrome: A case report
por: Murata, Tsuyoshi, et al.
Publicado: (2020)

Perinatal diagnosis of a fetus with an unbalanced translocation 46,XY,der(10)t(6;10)(p22;q26.1) with multiple malformations: a case report and literature review
por: Ishibashi, Makiho, et al.
Publicado: (2021)

A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells()
por: Hayakawa, Takao, et al.
Publicado: (2015)

A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of allogeneic human somatic stem cells()
por: Hayakawa, Takao, et al.
Publicado: (2015)

FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma
por: OKABE, NAOYUKI, et al.
Publicado: (2015)

Towards good correlation between fragment molecular orbital interaction energies and experimental IC(50) for ligand binding: A case study of p38 MAP kinase
por: Sheng, Yinglei, et al.
Publicado: (2018)

Clinical and reproductive outcomes of fertility-sparing surgery in stage I epithelial ovarian cancer
por: Watanabe, Takafumi, et al.
Publicado: (2020)

Somatic selection distinguishes oncogenes and tumor suppressor genes
por: Chandrashekar, Pramod, et al.
Publicado: (2019)

Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory
por: Monti, Noemi, et al.
Publicado: (2022)

Somatic recombination underlies frequent revertant mosaicism in loricrin keratoderma
por: Suzuki, Shotaro, et al.
Publicado: (2019)

Transforming somatic mutations of mammalian target of rapamycin kinase in human cancer
por: Yamaguchi, Hiroyuki, et al.
Publicado: (2015)

An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids
por: Takahashi, Nobuhiko, et al.
Publicado: (2019)

Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild-type epidermal growth factor receptor
por: Yamaura, Takumi, et al.
Publicado: (2018)

Risk of immunotherapy-related narcolepsy in genetically predisposed patients: a case report of narcolepsy after administration of pembrolizumab
por: Natori, Yutaka, et al.
Publicado: (2020)

A Novel Somatic Mutation in the RET Proto‐oncogene in Familial Medullary Thyroid Carcinoma with a Germline Codon 768 Mutation
por: Miyauchi, Akira, et al.
Publicado: (1997)

Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential
por: Yamato, Azusa, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_sh3idh6sa86jhupa3il1c1cj8f