Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines

The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective m...

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Detalles Bibliográficos
Autores principales: Lin, Weifeng, Yang, Zhen, Kaur, Amanpreet, Block, Annika, Vujasinovic, Miroslav, Löhr, J.-Matthias, Globisch, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496035/
https://www.ncbi.nlm.nih.gov/pubmed/34704052
http://dx.doi.org/10.1039/d1cb00132a
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author Lin, Weifeng
Yang, Zhen
Kaur, Amanpreet
Block, Annika
Vujasinovic, Miroslav
Löhr, J.-Matthias
Globisch, Daniel
author_facet Lin, Weifeng
Yang, Zhen
Kaur, Amanpreet
Block, Annika
Vujasinovic, Miroslav
Löhr, J.-Matthias
Globisch, Daniel
author_sort Lin, Weifeng
collection PubMed
description The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective moiety for amine metabolite analysis in human fecal samples.
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spelling pubmed-84960352021-10-25 Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines Lin, Weifeng Yang, Zhen Kaur, Amanpreet Block, Annika Vujasinovic, Miroslav Löhr, J.-Matthias Globisch, Daniel RSC Chem Biol Chemistry The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective moiety for amine metabolite analysis in human fecal samples. RSC 2021-08-12 /pmc/articles/PMC8496035/ /pubmed/34704052 http://dx.doi.org/10.1039/d1cb00132a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Lin, Weifeng
Yang, Zhen
Kaur, Amanpreet
Block, Annika
Vujasinovic, Miroslav
Löhr, J.-Matthias
Globisch, Daniel
Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
title Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
title_full Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
title_fullStr Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
title_full_unstemmed Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
title_short Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
title_sort squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496035/
https://www.ncbi.nlm.nih.gov/pubmed/34704052
http://dx.doi.org/10.1039/d1cb00132a
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