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Global properties of regulatory sequences are predicted by transcription factor recognition mechanisms
BACKGROUND: Mammalian genomes contain millions of putative regulatory sequences, which are delineated by binding of multiple transcription factors. The degree to which spacing and orientation constraints among transcription factor binding sites contribute to the recognition and identity of regulator...
Autores principales: | Patel, Zain M., Hughes, Timothy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496038/ https://www.ncbi.nlm.nih.gov/pubmed/34620190 http://dx.doi.org/10.1186/s13059-021-02503-y |
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