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Global properties of regulatory sequences are predicted by transcription factor recognition mechanisms

BACKGROUND: Mammalian genomes contain millions of putative regulatory sequences, which are delineated by binding of multiple transcription factors. The degree to which spacing and orientation constraints among transcription factor binding sites contribute to the recognition and identity of regulator...

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Detalles Bibliográficos
Autores principales: Patel, Zain M., Hughes, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496038/
https://www.ncbi.nlm.nih.gov/pubmed/34620190
http://dx.doi.org/10.1186/s13059-021-02503-y

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