Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma

BACKGROUND: Activation of the oncogene yes-associated protein (YAP) is frequently detected in intrahepatic cholangiocarcinoma (iCCA); however, the expression pattern and the functional impact of its paralogue WW domain-containing transcription regulator 1 (WWTR1; synonym: TAZ) are not well described...

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Detalles Bibliográficos
Autores principales: Tóth, Marcell, Wehling, Lilija, Thiess, Lena, Rose, Fabian, Schmitt, Jennifer, Weiler, Sofia M. E., Sticht, Carsten, De La Torre, Carolina, Rausch, Melina, Albrecht, Thomas, Grabe, Niels, Duwe, Lea, Andersen, Jesper B., Köhler, Bruno C., Springfeld, Christoph, Mehrabi, Arianeb, Kulu, Yakup, Schirmacher, Peter, Roessler, Stephanie, Goeppert, Benjamin, Breuhahn, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496054/
https://www.ncbi.nlm.nih.gov/pubmed/34615513
http://dx.doi.org/10.1186/s12885-021-08794-5

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