Receptor-specific Ca(2+) oscillation patterns mediated by differential regulation of P2Y purinergic receptors in rat hepatocytes

Extracellular agonists linked to inositol-1,4,5-trisphosphate (IP(3)) formation elicit cytosolic Ca(2+) oscillations in many cell types, but despite a common signaling pathway, distinct agonist-specific Ca(2+) spike patterns are observed. Using qPCR, we show that rat hepatocytes express multiple pur...

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Detalles Bibliográficos
Autores principales: Corrêa-Velloso, Juliana C., Bartlett, Paula J., Brumer, Robert, Gaspers, Lawrence D., Ulrich, Henning, Thomas, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496176/
https://www.ncbi.nlm.nih.gov/pubmed/34646983
http://dx.doi.org/10.1016/j.isci.2021.103139

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