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Targeted RNA-seq improves efficiency, resolution, and accuracy of allele specific expression for human term placentas

Genomic imprinting is an epigenetic mechanism that results in allele-specific expression (ASE) based on the parent of origin. It is known to play a role in the prenatal and postnatal allocation of maternal resources in mammals. ASE detected by whole transcriptome RNA-seq (wht-RNAseq) has been widely...

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Detalles Bibliográficos
Autores principales: Wu, Weisheng, Lovett, Jennie L, Shedden, Kerby, Strassmann, Beverly I, Vincenz, Claudius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496276/
https://www.ncbi.nlm.nih.gov/pubmed/34009305
http://dx.doi.org/10.1093/g3journal/jkab176

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