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An optimized ATAC-seq protocol for genome-wide mapping of active regulatory elements in primary mouse cortical neurons
ATAC-seq is a versatile, adaptable, and widely adopted technique for mapping open chromatin regions. However, some biological systems, such as primary neurons, present unique challenges to its application. Conventional ATAC-seq would require the dissociation of the primary neurons after plating but...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496302/ https://www.ncbi.nlm.nih.gov/pubmed/34647036 http://dx.doi.org/10.1016/j.xpro.2021.100854 |