An optimized ATAC-seq protocol for genome-wide mapping of active regulatory elements in primary mouse cortical neurons

ATAC-seq is a versatile, adaptable, and widely adopted technique for mapping open chromatin regions. However, some biological systems, such as primary neurons, present unique challenges to its application. Conventional ATAC-seq would require the dissociation of the primary neurons after plating but...

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Detalles Bibliográficos
Autores principales: Maor-Nof, Maya, Shipony, Zohar, Marinov, Georgi K., Greenleaf, William J., Gitler, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496302/
https://www.ncbi.nlm.nih.gov/pubmed/34647036
http://dx.doi.org/10.1016/j.xpro.2021.100854

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