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Quantification of natural abundance NMR data differentiates the solution behavior of monoclonal antibodies and their fragments
Biotherapeutics are an important class of molecules for the treatment of a wide range of diseases. They include low molecular weight peptides, highly engineered protein scaffolds and monoclonal antibodies. During their discovery and development, assessments of the biophysical attributes is critical...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496538/ https://www.ncbi.nlm.nih.gov/pubmed/34612804 http://dx.doi.org/10.1080/19420862.2021.1978132 |