BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation

Lipotoxicity is a form of cellular stress caused by the accumulation of lipids resulting in mitochondrial dysfunction and insulin resistance in muscle. Previously, we demonstrated that the mitophagy receptor BNIP3L/Nix is responsive to lipotoxicity and accumulates in response to a high-fat (HF) feed...

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Detalles Bibliográficos
Autores principales: da Silva Rosa, Simone C., Martens, Matthew D., Field, Jared T., Nguyen, Lucas, Kereliuk, Stephanie M., Hai, Yan, Chapman, Donald, Diehl-Jones, William, Aliani, Michel, West, Adrian R., Thliveris, James, Ghavami, Saeid, Rampitsch, Christof, Dolinsky, Vernon W., Gordon, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496715/
https://www.ncbi.nlm.nih.gov/pubmed/33044904
http://dx.doi.org/10.1080/15548627.2020.1821548

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