Impact of Changes of the 2020 Consensus Definitions of Invasive Aspergillosis on Clinical Trial Design: Unintended Consequences for Prevention Trials?

BACKGROUND: Consensus definitions for the diagnosis of invasive fungal diseases (IFDs) were updated in 2020 to increase the certainty of IFD for inclusion in clinical trials, for instance by increasing biomarker cutoff limits to define positivity. To date, there is a paucity of data as to the impact...

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Detalles Bibliográficos
Autores principales: Wingard, John R, Alexander, Barbara D, Baden, Lindsey R, Chen, Min, Sugrue, Michele W, Leather, Helen L, Caliendo, Angela M, Clancy, Cornelius J, Denning, David W, Marty, Francisco M, Nguyen, M Hong, Wheat, L Joseph, Logan, Brent R, Horowitz, Mary M, Marr, Kieren A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496761/
https://www.ncbi.nlm.nih.gov/pubmed/34631917
http://dx.doi.org/10.1093/ofid/ofab441

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