Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response

Dopamine (DA) neurons of the midbrain are at risk to become affected by mitochondrial damage over time and mitochondrial defects have been frequently reported in Parkinson’s disease (PD) patients. However, the causal contribution of adult-onset mitochondrial dysfunction to PD remains uncertain. Here...

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Detalles Bibliográficos
Autores principales: Filograna, Roberta, Lee, Seungmin, Tiklová, Katarína, Mennuni, Mara, Jonsson, Viktor, Ringnér, Markus, Gillberg, Linda, Sopova, Elena, Shupliakov, Oleg, Koolmeister, Camilla, Olson, Lars, Perlmann, Thomas, Larsson, Nils-Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496783/
https://www.ncbi.nlm.nih.gov/pubmed/34570766
http://dx.doi.org/10.1371/journal.pgen.1009822

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