Recurrent Germline Mutations of CHEK2 as a New Susceptibility Gene in Patients with Pheochromocytomas and Paragangliomas

PURPOSE: Recently, pheochromocytomas and paragangliomas (PPGLs) have been strongly suspected as hereditary tumors, as approximately 40% of patients carry germline mutations. In the cancers where defects occur to corrupt DNA repair and facilitate tumorigenesis, a CHEK2 strong association has been obs...

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Detalles Bibliográficos
Autores principales: Gao, Yinjie, Ling, Chao, Ma, Xiaosen, Wang, Huiping, Cui, Yunying, Nie, Min, Tong, Anli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497153/
https://www.ncbi.nlm.nih.gov/pubmed/34630562
http://dx.doi.org/10.1155/2021/1392386

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