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A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
BACKGROUND: Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear. METHODS AND RESULTS: We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventric...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497207/ https://www.ncbi.nlm.nih.gov/pubmed/34216106 http://dx.doi.org/10.1002/ehf2.13402 |
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author | Shah, Parin Abel, Alexandra A.I. Boyalla, Vennela Pellicori, Pierpaolo Kallvikbacka‐Bennett, Anna Sze, Shirley Cleland, John G.F. Clark, Andrew L. |
author_facet | Shah, Parin Abel, Alexandra A.I. Boyalla, Vennela Pellicori, Pierpaolo Kallvikbacka‐Bennett, Anna Sze, Shirley Cleland, John G.F. Clark, Andrew L. |
author_sort | Shah, Parin |
collection | PubMed |
description | BACKGROUND: Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear. METHODS AND RESULTS: We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventricular ejection fraction 44 (10) %, and median (Q1–Q3) N‐terminal pro B‐type natriuretic peptide 845 (355–1368) ng/L. We measured body composition using dual‐energy X‐ray absorptiometry (DEXA) and a multi‐frequency bioelectrical impedance analysis (BIA) device (Tanita BIA MC‐180MA). Mean (SD) fat mass (FM) was 27.2 (11.7) kg by BIA and 32.3 (12.2) kg by DEXA (mean difference −5.1 kg, 95% limits of agreement: −11.7, 1.5; 4% of values outside limit of agreement); mean (SD) lean mass (LM) was 56.6 (10.9) kg by BIA and 51.1 (9.9) kg by DEXA (mean difference 5.5 kg, 95% limits of agreement: −1.3, 12.3; 6% of values outside limit of agreement); and mean (SD) bone mass (BM) was 3.0 (0.5) kg by BIA and 2.8 (0.6) kg by DEXA (mean difference 0.2 kg, 95% limits of agreement: −0.5, 0.8; 5% of values outside limit of agreement). There was a close correlation between DEXA and BIA for both LM and FM (LM: r = 0.95, P < 0.001; FM: r = 0.96, P < 0.001) but less so for BM (r = 0.84, P < 0.001). Both DEXA and BIA body composition measurements correlated well with other measures of body size (body mass index, hip circumference, and waist circumference). CONCLUSIONS: There are differences in the measurements of FM, LM, and BM between the two techniques, which should not be used interchangeably. |
format | Online Article Text |
id | pubmed-8497207 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84972072021-10-12 A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF Shah, Parin Abel, Alexandra A.I. Boyalla, Vennela Pellicori, Pierpaolo Kallvikbacka‐Bennett, Anna Sze, Shirley Cleland, John G.F. Clark, Andrew L. ESC Heart Fail Original Research Articles BACKGROUND: Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear. METHODS AND RESULTS: We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventricular ejection fraction 44 (10) %, and median (Q1–Q3) N‐terminal pro B‐type natriuretic peptide 845 (355–1368) ng/L. We measured body composition using dual‐energy X‐ray absorptiometry (DEXA) and a multi‐frequency bioelectrical impedance analysis (BIA) device (Tanita BIA MC‐180MA). Mean (SD) fat mass (FM) was 27.2 (11.7) kg by BIA and 32.3 (12.2) kg by DEXA (mean difference −5.1 kg, 95% limits of agreement: −11.7, 1.5; 4% of values outside limit of agreement); mean (SD) lean mass (LM) was 56.6 (10.9) kg by BIA and 51.1 (9.9) kg by DEXA (mean difference 5.5 kg, 95% limits of agreement: −1.3, 12.3; 6% of values outside limit of agreement); and mean (SD) bone mass (BM) was 3.0 (0.5) kg by BIA and 2.8 (0.6) kg by DEXA (mean difference 0.2 kg, 95% limits of agreement: −0.5, 0.8; 5% of values outside limit of agreement). There was a close correlation between DEXA and BIA for both LM and FM (LM: r = 0.95, P < 0.001; FM: r = 0.96, P < 0.001) but less so for BM (r = 0.84, P < 0.001). Both DEXA and BIA body composition measurements correlated well with other measures of body size (body mass index, hip circumference, and waist circumference). CONCLUSIONS: There are differences in the measurements of FM, LM, and BM between the two techniques, which should not be used interchangeably. John Wiley and Sons Inc. 2021-07-03 /pmc/articles/PMC8497207/ /pubmed/34216106 http://dx.doi.org/10.1002/ehf2.13402 Text en © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Research Articles Shah, Parin Abel, Alexandra A.I. Boyalla, Vennela Pellicori, Pierpaolo Kallvikbacka‐Bennett, Anna Sze, Shirley Cleland, John G.F. Clark, Andrew L. A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF |
title | A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF |
title_full | A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF |
title_fullStr | A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF |
title_full_unstemmed | A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF |
title_short | A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF |
title_sort | comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from sica‐hf |
topic | Original Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497207/ https://www.ncbi.nlm.nih.gov/pubmed/34216106 http://dx.doi.org/10.1002/ehf2.13402 |
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