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A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF

BACKGROUND: Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear. METHODS AND RESULTS: We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventric...

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Autores principales: Shah, Parin, Abel, Alexandra A.I., Boyalla, Vennela, Pellicori, Pierpaolo, Kallvikbacka‐Bennett, Anna, Sze, Shirley, Cleland, John G.F., Clark, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497207/
https://www.ncbi.nlm.nih.gov/pubmed/34216106
http://dx.doi.org/10.1002/ehf2.13402
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author Shah, Parin
Abel, Alexandra A.I.
Boyalla, Vennela
Pellicori, Pierpaolo
Kallvikbacka‐Bennett, Anna
Sze, Shirley
Cleland, John G.F.
Clark, Andrew L.
author_facet Shah, Parin
Abel, Alexandra A.I.
Boyalla, Vennela
Pellicori, Pierpaolo
Kallvikbacka‐Bennett, Anna
Sze, Shirley
Cleland, John G.F.
Clark, Andrew L.
author_sort Shah, Parin
collection PubMed
description BACKGROUND: Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear. METHODS AND RESULTS: We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventricular ejection fraction 44 (10) %, and median (Q1–Q3) N‐terminal pro B‐type natriuretic peptide 845 (355–1368) ng/L. We measured body composition using dual‐energy X‐ray absorptiometry (DEXA) and a multi‐frequency bioelectrical impedance analysis (BIA) device (Tanita BIA MC‐180MA). Mean (SD) fat mass (FM) was 27.2 (11.7) kg by BIA and 32.3 (12.2) kg by DEXA (mean difference −5.1 kg, 95% limits of agreement: −11.7, 1.5; 4% of values outside limit of agreement); mean (SD) lean mass (LM) was 56.6 (10.9) kg by BIA and 51.1 (9.9) kg by DEXA (mean difference 5.5 kg, 95% limits of agreement: −1.3, 12.3; 6% of values outside limit of agreement); and mean (SD) bone mass (BM) was 3.0 (0.5) kg by BIA and 2.8 (0.6) kg by DEXA (mean difference 0.2 kg, 95% limits of agreement: −0.5, 0.8; 5% of values outside limit of agreement). There was a close correlation between DEXA and BIA for both LM and FM (LM: r = 0.95, P < 0.001; FM: r = 0.96, P < 0.001) but less so for BM (r = 0.84, P < 0.001). Both DEXA and BIA body composition measurements correlated well with other measures of body size (body mass index, hip circumference, and waist circumference). CONCLUSIONS: There are differences in the measurements of FM, LM, and BM between the two techniques, which should not be used interchangeably.
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spelling pubmed-84972072021-10-12 A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF Shah, Parin Abel, Alexandra A.I. Boyalla, Vennela Pellicori, Pierpaolo Kallvikbacka‐Bennett, Anna Sze, Shirley Cleland, John G.F. Clark, Andrew L. ESC Heart Fail Original Research Articles BACKGROUND: Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear. METHODS AND RESULTS: We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventricular ejection fraction 44 (10) %, and median (Q1–Q3) N‐terminal pro B‐type natriuretic peptide 845 (355–1368) ng/L. We measured body composition using dual‐energy X‐ray absorptiometry (DEXA) and a multi‐frequency bioelectrical impedance analysis (BIA) device (Tanita BIA MC‐180MA). Mean (SD) fat mass (FM) was 27.2 (11.7) kg by BIA and 32.3 (12.2) kg by DEXA (mean difference −5.1 kg, 95% limits of agreement: −11.7, 1.5; 4% of values outside limit of agreement); mean (SD) lean mass (LM) was 56.6 (10.9) kg by BIA and 51.1 (9.9) kg by DEXA (mean difference 5.5 kg, 95% limits of agreement: −1.3, 12.3; 6% of values outside limit of agreement); and mean (SD) bone mass (BM) was 3.0 (0.5) kg by BIA and 2.8 (0.6) kg by DEXA (mean difference 0.2 kg, 95% limits of agreement: −0.5, 0.8; 5% of values outside limit of agreement). There was a close correlation between DEXA and BIA for both LM and FM (LM: r = 0.95, P < 0.001; FM: r = 0.96, P < 0.001) but less so for BM (r = 0.84, P < 0.001). Both DEXA and BIA body composition measurements correlated well with other measures of body size (body mass index, hip circumference, and waist circumference). CONCLUSIONS: There are differences in the measurements of FM, LM, and BM between the two techniques, which should not be used interchangeably. John Wiley and Sons Inc. 2021-07-03 /pmc/articles/PMC8497207/ /pubmed/34216106 http://dx.doi.org/10.1002/ehf2.13402 Text en © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research Articles
Shah, Parin
Abel, Alexandra A.I.
Boyalla, Vennela
Pellicori, Pierpaolo
Kallvikbacka‐Bennett, Anna
Sze, Shirley
Cleland, John G.F.
Clark, Andrew L.
A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
title A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
title_full A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
title_fullStr A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
title_full_unstemmed A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
title_short A comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from SICA‐HF
title_sort comparison of non‐invasive methods of measuring body composition in patients with heart failure: a report from sica‐hf
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497207/
https://www.ncbi.nlm.nih.gov/pubmed/34216106
http://dx.doi.org/10.1002/ehf2.13402
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