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RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells

The activity of Rho family GTPase protein, RAC1, which plays important normal physiological functions, is dysregulated in multiple cancers. RAC1 is expressed in both estrogen receptor alpha (ER)-positive and ER-negative breast cancer (BC) cells. However, ER-positive BC is more sensitive to RAC1 inhi...

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Detalles Bibliográficos
Autores principales:	Sun, Jun, Gaidosh, Gabriel, Xu, Ye, Mookhtiar, Adnan, Man, Na, Cingaram, Pradeep Reddy, Blumenthal, Ezra, Shiekhattar, Ramin, Goka, Erik T., Nimer, Stephen D., Lippman, Marc E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497275/ https://www.ncbi.nlm.nih.gov/pubmed/34373577 http://dx.doi.org/10.1038/s41388-021-01985-1

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