W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34

Spinocerebellar ataxia (SCA) is a neurodegenerative disorder characterized by ataxia and cerebellar atrophy. A number of different mutations gives rise to different types of SCA with characteristic ages of onset, symptomatology, and rates of progression. SCA type 34 (SCA34) is caused by mutations in...

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Detalles Bibliográficos
Autores principales: Nagaraja, Raghavendra Y., Sherry, David M., Fessler, Jennifer L., Stiles, Megan A., Li, Feng, Multani, Karanpreet, Orock, Albert, Ahmad, Mohiuddin, Brush, Richard S., Anderson, Robert E., Agbaga, Martin-Paul, Deák, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497303/
https://www.ncbi.nlm.nih.gov/pubmed/34227061
http://dx.doi.org/10.1007/s12035-021-02439-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497303/
https://www.ncbi.nlm.nih.gov/pubmed/34227061
http://dx.doi.org/10.1007/s12035-021-02439-1

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