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Identification of phosphoenolpyruvate carboxykinase 1 as a potential therapeutic target for pancreatic cancer

Pancreatic cancer is the third leading cause of cancer-related mortalities and is characterized by rapid disease progression. Identification of novel therapeutic targets for this devastating disease is important. Phosphoenolpyruvate carboxykinase 1 (PCK1) is the rate-limiting enzyme of gluconeogenes...

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Detalles Bibliográficos
Autores principales: Zhu, Xiao-ren, Peng, Shi-qing, Wang, Le, Chen, Xiao-yu, Feng, Chun-xia, Liu, Yuan-yuan, Chen, Min-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497628/
https://www.ncbi.nlm.nih.gov/pubmed/34620839
http://dx.doi.org/10.1038/s41419-021-04201-w

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