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Higenamine Attenuates Neuropathic Pain by Inhibition of NOX2/ROS/TRP/P38 Mitogen-Activated Protein Kinase/NF-ĸB Signaling Pathway

Oxidative stress damage is known as one of the important factors that induce neuropathic pain (NP). Using antioxidant therapy usually achieves an obvious curative effect and alleviates NP. Previous pharmacological studies have shown that higenamine (Hig) performs to be antioxidant and anti-inflammat...

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Detalles Bibliográficos
Autores principales: Yang, Bing, Ma, Shengsuo, Zhang, Chunlan, Sun, Jianxin, Zhang, Di, Chang, Shiquan, Lin, Yi, Zhao, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497786/
https://www.ncbi.nlm.nih.gov/pubmed/34630095
http://dx.doi.org/10.3389/fphar.2021.716684