Cargando…

Rivaroxaban Modulates TLR4/Myd88/NF-Kβ Signaling Pathway in a Dose-Dependent Manner With Suppression of Oxidative Stress and Inflammation in an Experimental Model of Depression

Depression is a common mental illness leading to upset or anxiety, with a high incidence rate in the world. Depression can lead to suicidal thoughts and behavior. The present study aimed to evaluate the effect of the direct oral anticoagulant rivaroxaban (RVX), in the model of depression induced by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdelzaher, Walaa Yehia, Mohammed, Hanaa H., Welson, Nermeen N., Batiha, Gaber El-Saber, Baty, Roua S., Abdel-Aziz, Asmaa Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497790/ https://www.ncbi.nlm.nih.gov/pubmed/34630092 http://dx.doi.org/10.3389/fphar.2021.715354

Ejemplares similares

Xanthine Oxidase Inhibitor, Febuxostat Is Effective against 5-Fluorouracil-Induced Parotid Salivary Gland Injury in Rats Via Inhibition of Oxidative Stress, Inflammation and Targeting TRPC1/CHOP Signalling Pathway
por: Abdelzaher, Walaa Yehia, et al.
Publicado: (2022)

Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-α Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats
por: Abdelzaher, Walaa Yehia, et al.
Publicado: (2021)

Diacerein modulates TLR4/ NF‐κB/IL‐1β and TRPC1/CHOP signalling pathways in gentamicin‐induced parotid toxicity in rats
por: Ali, Dalia Mohamed, et al.
Publicado: (2023)

Role of Platelet-activating factor and HO-1 in mediating the protective effect of rupatadine against 5-fluorouracil-induced hepatotoxicity in rats
por: Khalaf, Hanaa Mohamed, et al.
Publicado: (2022)

Mycobacterium indicus pranii therapy induces tumor regression in MyD88- and TLR2-dependent manner
por: Kumar, Pawan, et al.
Publicado: (2019)

Paeonol Attenuates Hepatic Ischemia/Reperfusion Injury by Modulating the Nrf2/HO-1 and TLR4/MYD88/NF-κB Signaling Pathways
por: Morsy, Mohamed A., et al.
Publicado: (2022)

Empagliflozin Protects against Haloperidol Experimentally-Induced Ovarian Toxicity
por: Abdelzaher, Walaa Yehia, et al.
Publicado: (2023)

Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats
por: Rofaeil, Remon Roshdy, et al.
Publicado: (2022)

Trimetazidine and COVID-19-induced acute cardiac injury: a missed key
por: Al-kuraishy, Hayder M., et al.
Publicado: (2022)

Pathophysiology of Post-COVID syndromes: a new perspective
por: Batiha, Gaber El-Saber, et al.
Publicado: (2022)

Tumor-Derived Autophagosomes (DRibbles) Induce B Cell Activation in a TLR2-MyD88 Dependent Manner
por: Li, Weixia, et al.
Publicado: (2013)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

The Effect of TLR9, MyD88, and NF-κB p65 in Systemic Lupus Erythematosus
por: Wang, Huanan, et al.
Publicado: (2022)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

MyD88 promotes myoblast fusion in a cell-autonomous manner
por: Hindi, Sajedah M., et al.
Publicado: (2017)

Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia
por: Fan, Hongguang, et al.
Publicado: (2009)

Exercise Therapy Downregulates the Overexpression of TLR4, TLR2, MyD88 and NF-κB after Cerebral Ischemia in Rats
por: Ma, Yuewen, et al.
Publicado: (2013)

Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
por: Li, Chengcheng, et al.
Publicado: (2017)

The role of TLR4/MyD88/NF‐κB pathway in periodontitis‐induced liver inflammation of rats
por: Yue, Yiyun, et al.
Publicado: (2020)

Lack of Associations between TLR9 and MYD88 Gene Polymorphisms and Risk of Chronic Lymphocytic Leukemia
por: Ali, Yasser B.M, et al.
Publicado: (2017)

Leukotriene Receptor Antagonist, Montelukast Ameliorates L-NAME-Induced Pre-eclampsia in Rats through Suppressing the IL-6/Jak2/STAT3 Signaling Pathway
por: Abdelzaher, Walaa Yehia, et al.
Publicado: (2022)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

Baishouwu Extract Suppresses the Development of Hepatocellular Carcinoma via TLR4/MyD88/NF-κB Pathway
por: Ding, Yong-fang, et al.
Publicado: (2019)

Expressions of TLR4, MyD88, IRAK4 and NF-ÎB in the oviduct of Chinese brown frog (Rana dybowskii)
por: Zhang, Yue, et al.
Publicado: (2019)

Lipoxin suppresses inflammation via the TLR4/MyD88/NF‐κB pathway in periodontal ligament cells
por: Ali, Muhanad, et al.
Publicado: (2019)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

Impact of domestic violence against pregnant women in Minia governorate, Egypt: a cross sectional study
por: Elkhateeb, Reham, et al.
Publicado: (2021)

Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling
por: Wu, Li-Rong, et al.
Publicado: (2017)

Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling
por: Gao, Jin-meng, et al.
Publicado: (2017)

LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway
por: Zhong, Yu, et al.
Publicado: (2020)

Exercise Training Attenuates Hypertension Through TLR4/MyD88/NF-κB Signaling in the Hypothalamic Paraventricular Nucleus
por: Qi, Jie, et al.
Publicado: (2019)

The TLR4-MyD88-NF-κB pathway is involved in sIgA-mediated IgA nephropathy
por: Zhang, Junjun, et al.
Publicado: (2020)

Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo
por: Dutta, Debashis, et al.
Publicado: (2021)

The Protective Effect of Anethole against Renal Ischemia/Reperfusion: The Role of the TLR2,4/MYD88/NFκB Pathway
por: Mohamed, Maged Elsayed, et al.
Publicado: (2022)

Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora
por: Zhan, Lianghui, et al.
Publicado: (2022)

Aberrant Expression of TLR2, TLR7, TLR9, Splicing Variants of TLR4 and MYD88 in Chronic Lymphocytic Leukemia Patients
por: Skorka, Katarzyna, et al.
Publicado: (2021)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Sakai, Jiro, et al.
Publicado: (2017)

Receptor-dependent effects of sphingosine-1-phosphate (S1P) in COVID-19: the black side of the moon
por: Al-kuraishy, Hayder M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_btu067nv8vvre0fe7g55m0340l