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Experimental Study of Almonertinib Crossing the Blood-Brain Barrier in EGFR-Mutant NSCLC Brain Metastasis and Spinal Cord Metastasis Models

Roughly one third of non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI)-sensitive mutated (EGFRm) tumors experience disease progression through central nervous system (CNS) metastases during treatment. Although EGFR-TKIs have been r...

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Detalles Bibliográficos
Autores principales:	Zhang, Yuhan, Zhang, Yaoshuai, Niu, Wenwen, Ge, Xianming, Huang, Fuhao, Pang, Jinlong, Li, Xian, Wang, Yu, Gao, Wei, Fan, Fangtian, Li, Shanshan, Liu, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497791/ https://www.ncbi.nlm.nih.gov/pubmed/34630120 http://dx.doi.org/10.3389/fphar.2021.750031

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