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LINC01001 Promotes Progression of Crizotinib-Resistant NSCLC by Modulating IGF2BP2/MYC Axis

Background: Crizotinib is a microtubule-related protein-4-anaplastic lymphoma kinase (EML4-ALK) multi-target tyrosine kinase inhibitor applied in the treatment of ALK-rearranged NSCLC. However, the specific molecular mechanism underlying its therapeutic effect remains unclear. Therefore, the purpose...

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Detalles Bibliográficos
Autores principales:	Zhang, Meiling, Wang, Qian, Ke, Zihao, Liu, Yijing, Guo, Huijin, Fang, Shencun, Lu, Kaihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497803/ https://www.ncbi.nlm.nih.gov/pubmed/34630126 http://dx.doi.org/10.3389/fphar.2021.759267

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