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T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells

T-bet and Eomes are transcription factors that are known to be important in maturation and function of murine natural killer (NK) cells. Reduced T-BET and EOMES expression results in dysfunctional NK cells and failure to control tumor growth. In contrast to mice, the current knowledge on the role of...

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Detalles Bibliográficos
Autores principales:	Kiekens, Laura, Van Loocke, Wouter, Taveirne, Sylvie, Wahlen, Sigrid, Persyn, Eva, Van Ammel, Els, De Vos, Zenzi, Matthys, Patrick, Van Nieuwerburgh, Filip, Taghon, Tom, Van Vlierberghe, Pieter, Vandekerckhove, Bart, Leclercq, Georges
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497824/ https://www.ncbi.nlm.nih.gov/pubmed/34630413 http://dx.doi.org/10.3389/fimmu.2021.732511

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