Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pulposus cells through the nuclear factor‐kappa B pathway

OBJECTIVE: To investigate the protective effect and mechanism of shikonin on human intervertebral disk degeneration. METHODS: Human primary nucleus pulposus (NP) cells cultured in vitro were used for the experiments. The effects of different concentrations of shikonin (1, 2, 4, 8, and 16 µM) on the...

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Detalles Bibliográficos
Autores principales: Liu, Yuanbin, Zheng, Jiazhuang, Chen, Yu, Wang, Fandong, Ye, He, Wang, Miao, Zhang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497831/
https://www.ncbi.nlm.nih.gov/pubmed/34646528
http://dx.doi.org/10.1002/fsn3.2519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497831/
https://www.ncbi.nlm.nih.gov/pubmed/34646528
http://dx.doi.org/10.1002/fsn3.2519

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