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Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes

Xanthomonas Oryzae pv. oryzae (Xoo) causes bacterial blight and Rhizoctonia solani (R. solani) causes sheath blight in rice accounting for >75% of crop losses. Therefore, there is an urgent need to develop strategies for the mitigation of these pathogen infections. In this study, we report the an...

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Autores principales: Pal, Garima, Mehta, Devashish, Singh, Saurabh, Magal, Kalai, Gupta, Siddhi, Jha, Gopaljee, Bajaj, Avinash, Ramu, Vemanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497891/
https://www.ncbi.nlm.nih.gov/pubmed/34630495
http://dx.doi.org/10.3389/fpls.2021.746912
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author Pal, Garima
Mehta, Devashish
Singh, Saurabh
Magal, Kalai
Gupta, Siddhi
Jha, Gopaljee
Bajaj, Avinash
Ramu, Vemanna S.
author_facet Pal, Garima
Mehta, Devashish
Singh, Saurabh
Magal, Kalai
Gupta, Siddhi
Jha, Gopaljee
Bajaj, Avinash
Ramu, Vemanna S.
author_sort Pal, Garima
collection PubMed
description Xanthomonas Oryzae pv. oryzae (Xoo) causes bacterial blight and Rhizoctonia solani (R. solani) causes sheath blight in rice accounting for >75% of crop losses. Therefore, there is an urgent need to develop strategies for the mitigation of these pathogen infections. In this study, we report the antimicrobial efficacy of Cholic Acid-Glycine Conjugates (CAGCs) against Xoo and R. solani. We show that CAGC C6 is a broad-spectrum antimicrobial and is also able to degrade biofilms. The application of C6 did not hamper plant growth and showed minimal effect on the plant cell membranes. Exogenous application of C6 on pre-infection or post-infection of Xoo on rice susceptible genotype Taichung native (TN1) can mitigate the bacterial load and improve resistance through upregulation of plant defense genes. We further demonstrate that C6 can induce plant defense responses when seeds were primed with C6 CAGC. Therefore, this study demonstrates the potential of CAGCs as effective antimicrobials for crop protection that can be further explored for field applications.
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spelling pubmed-84978912021-10-09 Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes Pal, Garima Mehta, Devashish Singh, Saurabh Magal, Kalai Gupta, Siddhi Jha, Gopaljee Bajaj, Avinash Ramu, Vemanna S. Front Plant Sci Plant Science Xanthomonas Oryzae pv. oryzae (Xoo) causes bacterial blight and Rhizoctonia solani (R. solani) causes sheath blight in rice accounting for >75% of crop losses. Therefore, there is an urgent need to develop strategies for the mitigation of these pathogen infections. In this study, we report the antimicrobial efficacy of Cholic Acid-Glycine Conjugates (CAGCs) against Xoo and R. solani. We show that CAGC C6 is a broad-spectrum antimicrobial and is also able to degrade biofilms. The application of C6 did not hamper plant growth and showed minimal effect on the plant cell membranes. Exogenous application of C6 on pre-infection or post-infection of Xoo on rice susceptible genotype Taichung native (TN1) can mitigate the bacterial load and improve resistance through upregulation of plant defense genes. We further demonstrate that C6 can induce plant defense responses when seeds were primed with C6 CAGC. Therefore, this study demonstrates the potential of CAGCs as effective antimicrobials for crop protection that can be further explored for field applications. Frontiers Media S.A. 2021-09-24 /pmc/articles/PMC8497891/ /pubmed/34630495 http://dx.doi.org/10.3389/fpls.2021.746912 Text en Copyright © 2021 Pal, Mehta, Singh, Magal, Gupta, Jha, Bajaj and Ramu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Pal, Garima
Mehta, Devashish
Singh, Saurabh
Magal, Kalai
Gupta, Siddhi
Jha, Gopaljee
Bajaj, Avinash
Ramu, Vemanna S.
Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes
title Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes
title_full Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes
title_fullStr Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes
title_full_unstemmed Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes
title_short Foliar Application or Seed Priming of Cholic Acid-Glycine Conjugates can Mitigate/Prevent the Rice Bacterial Leaf Blight Disease via Activating Plant Defense Genes
title_sort foliar application or seed priming of cholic acid-glycine conjugates can mitigate/prevent the rice bacterial leaf blight disease via activating plant defense genes
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497891/
https://www.ncbi.nlm.nih.gov/pubmed/34630495
http://dx.doi.org/10.3389/fpls.2021.746912
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