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Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells

The cellular effects of hydrogen sulfide (H(2)S) signaling may be partially mediated by the formation of alkyl persulfides from thiols, such as glutathione and protein cysteine residues. Persulfides are potent nucleophiles and reductants and therefore potentially an important endogenous antioxidant...

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Detalles Bibliográficos
Autores principales: Switzer, Christopher H., Guttzeit, Sebastian, Eykyn, Thomas R., Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497997/
https://www.ncbi.nlm.nih.gov/pubmed/34607161
http://dx.doi.org/10.1016/j.redox.2021.102155

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