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Molecular mechanism of interactions between ACAD9 and binding partners in mitochondrial respiratory complex I assembly
The dual function protein ACAD9 catalyzes α,β-dehydrogenation of fatty acyl-CoA thioesters in fatty acid β-oxidation and is an essential chaperone for mitochondrial respiratory complex I (CI) assembly. ACAD9, ECSIT, and NDUFAF1 interact to form the core mitochondrial CI assembly complex. Current stu...
Autores principales: | Xia, Chuanwu, Lou, Baoying, Fu, Zhuji, Mohsen, Al-Walid, Shen, Anna L., Vockley, Jerry, Kim, Jung-Ja P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497999/ https://www.ncbi.nlm.nih.gov/pubmed/34646991 http://dx.doi.org/10.1016/j.isci.2021.103153 |
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