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Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance

BACKGROUND & AIMS: Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes mellitus in humans. Bilirubin has antioxidant and anti-inflammatory activi...

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Detalles Bibliográficos
Autores principales: Chen, Weiyu, Tumanov, Sergey, Fazarkeley, Daniel, Cantley, James, James, David E., Dunn, Louise L., Shaik, Taqi, Suarna, Cacang, Stocker, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498001/
https://www.ncbi.nlm.nih.gov/pubmed/34610553
http://dx.doi.org/10.1016/j.redox.2021.102152

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