Cargando…

Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance

BACKGROUND & AIMS: Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes mellitus in humans. Bilirubin has antioxidant and anti-inflammatory activi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Weiyu, Tumanov, Sergey, Fazarkeley, Daniel, Cantley, James, James, David E., Dunn, Louise L., Shaik, Taqi, Suarna, Cacang, Stocker, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498001/ https://www.ncbi.nlm.nih.gov/pubmed/34610553 http://dx.doi.org/10.1016/j.redox.2021.102152

Ejemplares similares

Near-Infrared Autofluorescence (NIRAF) in Atherosclerotic Plaque Dissociates from Intraplaque Hemorrhage and Bilirubin
por: Chen, Weiyu, et al.
Publicado: (2023)

Behavioral and cognitive data in mice with different tryptophan-metabolizing enzymes knocked out
por: Too, Lay Khoon, et al.
Publicado: (2016)

Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP
por: Sobti, Meghna, et al.
Publicado: (2019)

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q
por: Ayer, Anita, et al.
Publicado: (2021)

Therapeutic inhibition of MPO stabilizes pre-existing high risk atherosclerotic plaque
por: Chen, Weiyu, et al.
Publicado: (2022)

Microglia Susceptibility to Free Bilirubin Is Age-Dependent
por: Vaz, Ana Rita, et al.
Publicado: (2020)

Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance
por: Edmunds, Lia R., et al.
Publicado: (2020)

Differentiation renders susceptibility to excitotoxicity in HT22 neurons☆
por: He, Minchao, et al.
Publicado: (2013)

Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate
por: Hinds, Terry D., et al.
Publicado: (2020)

EBV renders B cells susceptible to HIV-1 in humanized mice
por: McHugh, Donal, et al.
Publicado: (2020)

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization
por: Powell, Allison B., et al.
Publicado: (2019)

Case Report: High-concentration Insulin Glargine Overdose Complicated by Hepatic Steatosis
por: Endall, Ryan, et al.
Publicado: (2020)

Rendering for beginners: image synthesis using RenderMan
por: Raghavachary, Saty
Publicado: (2004)

Rendering algorithms for aberrated human vision simulation
por: Csoba, István, et al.
Publicado: (2023)

Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice
por: Bortolussi, Giulia, et al.
Publicado: (2014)

Insulin resistance, steatosis and hepatitis C virus
por: Mangia, Alessandra, et al.
Publicado: (2013)

Hepatitis C Virus, Insulin Resistance, and Steatosis
por: Kralj, Dominik, et al.
Publicado: (2016)

Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
por: Takei, Ryoko, et al.
Publicado: (2019)

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration
por: Cebrián, Carolina, et al.
Publicado: (2014)

Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
por: Krieg, Carsten, et al.
Publicado: (2022)

ATLAS Rendered
Publicado: (2009)

Justice Rendered
Publicado: (1878)

For Services Rendered
Publicado: (1875)

Exposure Render: An Interactive Photo-Realistic Volume Rendering Framework
por: Kroes, Thomas, et al.
Publicado: (2012)

Integrative processing of untargeted metabolomic and lipidomic data using MultiABLER
por: Lee, Ian C.H., et al.
Publicado: (2023)

Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?
por: Cantley, James, et al.
Publicado: (2015)

The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates
por: Fernández-Coll, Llorenç, et al.
Publicado: (2020)

Correction to: Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?
por: Cantley, James, et al.
Publicado: (2019)

Physical activity and total serum bilirubin levels among insulin sensitive and insulin resistant U.S. adults
por: Loprinzi, Paul D, et al.
Publicado: (2014)

Designed α-sheet peptides disrupt uropathogenic E. coli biofilms rendering bacteria susceptible to antibiotics and immune cells
por: Bleem, Alissa, et al.
Publicado: (2023)

Correction: Exposure Render: An Interactive Photo-Realistic Volume Rendering Framework
por: Kroes, Thomas, et al.
Publicado: (2013)

Molecular mechanisms involved in hepatic steatosis and insulin resistance
por: Matsuzaka, Takashi, et al.
Publicado: (2011)

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
por: Li, Ying, et al.
Publicado: (2022)

Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis
por: Kaushansky, A, et al.
Publicado: (2013)

Antimicrobial Peptide Induced-Stress Renders Staphylococcus aureus Susceptible to Toxic Nucleoside Analogs
por: Rodríguez-Rojas, Alexandro, et al.
Publicado: (2020)

An Osmotic Laxative Renders Mice Susceptible to Prolonged Clostridioides difficile Colonization and Hinders Clearance
por: Tomkovich, Sarah, et al.
Publicado: (2021)

Praziquantel Treatment of Schistosoma mansoni Infected Mice Renders Them Less Susceptible to Reinfection
por: Nono, Justin Komguep, et al.
Publicado: (2021)

Role of Patatin-Like Phospholipase Domain-Containing 3 on Lipid-Induced Hepatic Steatosis and Insulin Resistance in Rats
por: Kumashiro, Naoki, et al.
Publicado: (2013)

The use of transcutaneous bilirubin nomograms for the prevention of bilirubin neurotoxicity in the neonates
por: Casnocha Lucanova, Lucia, et al.
Publicado: (2023)

Practical parallel rendering
por: Chalmers, Alan, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_u9jpfd87rbh193u3t6stusfgpn