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Food phytochemicals, epigallocatechin gallate and myricetin, covalently bind to the active site of the coronavirus main protease in vitro

SARS-CoV-2 main protease is a possible target for protection against viral infection. This study examined the inhibitory effect of food phytochemicals on the main protease of SARS-CoV-2 by determining a cleaved product after chromatographic separation. First, 37 phytochemicals, including glycosides...

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Detalles Bibliográficos
Autores principales: Kato, Yoji, Higashiyama, Akari, Takaoka, Emi, Nishikawa, Miyu, Ikushiro, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498006/
https://www.ncbi.nlm.nih.gov/pubmed/35425933
http://dx.doi.org/10.1016/j.arres.2021.100021