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Low Soluble Programmed Cell Death Protein 1 Levels After Allogeneic Stem Cell Transplantation Predict Moderate or Severe Chronic GvHD and Inferior Overall Survival

Programmed cell death protein-1 (PD-1) is an inhibitory co-receptor required for regulating immune responsiveness and maintaining immune homeostasis. As PD-1 can be released as bioactive soluble molecule, we investigated the clinical significance of soluble PD-1 (sPD-1) after allogeneic hematopoieti...

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Detalles Bibliográficos
Autores principales: Kordelas, Lambros, Buttkereit, Ulrike, Heinemann, Falko M., Horn, Peter A., Giebel, Bernd, Beelen, Dietrich W., Reinhardt, H. Christian, Rebmann, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498033/
https://www.ncbi.nlm.nih.gov/pubmed/34630383
http://dx.doi.org/10.3389/fimmu.2021.694843