Cargando…

Fractions of Shen-Sui-Tong-Zhi Formula Enhance Osteogenesis Via Activation of β-Catenin Signaling in Growth Plate Chondrocytes

Background: Shen-sui-tong-zhi formula (SSTZF) has been used to treat osteoporosis for decades and shows excellent clinical efficacy. This article aims to explore the optimal anti-osteoporotic ingredient and its precise mechanisms in mice models. Methods: In this study, we first screened the optimal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Rui, Zeng, Qinghe, Xia, Chenjie, Chen, Jiali, Wang, Pinger, Zhao, Shan, Yuan, Wenhua, Lou, Zhaohuan, Lin, Houfu, Xia, Hanting, Lv, Shuaijie, Xu, Taotao, Tong, Peijian, Gu, Mancang, Jin, Hongting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498212/ https://www.ncbi.nlm.nih.gov/pubmed/34630086 http://dx.doi.org/10.3389/fphar.2021.711004

Ejemplares similares

Osteoking Decelerates Cartilage Degeneration in DMM-Induced Osteoarthritic Mice Model Through TGF-β/smad-dependent Manner
por: Ling, Houfu, et al.
Publicado: (2021)

Wen-Shen-Tong-Luo-Zhi-Tong Decoction regulates bone–fat balance in osteoporosis by adipocyte-derived exosomes
por: Wang, Lining, et al.
Publicado: (2023)

N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling
por: Zeng, Qinghe, et al.
Publicado: (2022)

Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH
por: Xu, Huihui, et al.
Publicado: (2023)

Col9a2 gene deletion accelerates the degeneration of intervertebral discs
por: Xu, Huihui, et al.
Publicado: (2022)

Effect of Yin-Xing-Tong-Zhi Tablets on Improving Vascular Cognitive Impairment No Dementia
por: Pan, Weidong, et al.
Publicado: (2018)

Pharmaceutical and pharmacological studies of Shen Ma Yi Zhi granule for prevention of vascular dementia: A review
por: Chang, Su-rui, et al.
Publicado: (2022)

Disruption of Col9a2 expression leads to defects in osteochondral homeostasis and osteoarthritis-like phenotype in mice
por: Dong, Rui, et al.
Publicado: (2023)

Systematic Review of Basic Research on Alzheimer's Disease with Shen Zhi Ling Oral Liquid
por: Wang, Yahan, et al.
Publicado: (2019)

Bushenhuoxue Formula Facilitates Articular Cartilage Repair and Attenuates Matrix Degradation by Activation of TGF-β Signaling Pathway
por: Dong, Rui, et al.
Publicado: (2018)

Shen-Zhi-Ling Oral Liquid Improves Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease
por: Pan, Weidong, et al.
Publicado: (2014)

Integrated Strategy of Network Pharmacological Prediction and Experimental Validation Elucidate Possible Mechanism of Bu-Yang Herbs in Treating Postmenopausal Osteoporosis via ESR1
por: Xia, Hanting, et al.
Publicado: (2021)

Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography
por: Yang, Xing-Xin, et al.
Publicado: (2011)

A Network Pharmacology Approach to Explore the Mechanism of HuangZhi YiShen Capsule for Treatment of Diabetic Kidney Disease
por: Zhou, Xue-Feng, et al.
Publicado: (2021)

Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease
por: Iyaswamy, A., et al.
Publicado: (2020)

Defining disease progression in Chinese mainland people: Association between bone mineral density and knee osteoarthritis
por: Fang, Liang, et al.
Publicado: (2020)

Genome‐wide microRNA screening reveals miR‐582‐5p as a mesenchymal stem cell‐specific microRNA in subchondral bone of the human knee joint
por: Wang, Pinger, et al.
Publicado: (2019)

The Fate and Distribution of Autologous Bone Marrow Mesenchymal Stem Cells with Intra-Arterial Infusion in Osteonecrosis of the Femoral Head in Dogs
por: Jin, Hongting, et al.
Publicado: (2016)

Hainan zhi wu zhi /
Publicado: (1964)

Amygdalin Promotes Fracture Healing through TGF-β/Smad Signaling in Mesenchymal Stem Cells
por: Ying, Jun, et al.
Publicado: (2020)

Osthole Promotes Bone Fracture Healing through Activation of BMP Signaling in Chondrocytes
por: Wang, Pinger, et al.
Publicado: (2017)

Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice
por: Xu, Taotao, et al.
Publicado: (2017)

A Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial of Qi-Zhi-Wei-Tong Granules on Postprandial Distress Syndrome-Predominant Functional Dyspepsia
por: Su, Qing, et al.
Publicado: (2018)

An Shen Ding Zhi Ling Alleviates Symptoms of Attention Deficit Hyperactivity Disorder via Anti-Inflammatory Effects in Spontaneous Hypertensive Rats
por: Song, Yuchen, et al.
Publicado: (2021)

BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease
por: Guo, Yifan, et al.
Publicado: (2023)

Amygdalin Delays Cartilage Endplate Degeneration and Improves Intervertebral Disc Degeneration by Inhibiting NF-κB Signaling Pathway and Inflammatory Response
por: Zeng, Qinghe, et al.
Publicado: (2023)

Elucidation of the Underlying Mechanism of Gujian Oral Liquid Acting on Osteoarthritis through Network Pharmacology, Molecular Docking, and Experiment
por: Wu, Congzi, et al.
Publicado: (2022)

Corrigendum: A Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial of Qi-Zhi-Wei-Tong Granules on Postprandial Distress Syndrome-Predominant Functional Dyspepsia
Publicado: (2019)

TGF‐β/Smad2 signalling regulates enchondral bone formation of Gli1(+) periosteal cells during fracture healing
por: Xia, Chenjie, et al.
Publicado: (2020)

Bioconversion of Ginsenosides in the American Ginseng (西洋參 Xī Yáng Shēn) Extraction Residue by Fermentation with Lingzhi (靈芝 Líng Zhī, Ganoderma Lucidum)
por: Yang Hsu, Bo, et al.
Publicado: (2013)

Effect of BuShen JiangZhi Recipe on Atherosclerosis in ApoE(−/-) Mice by Regulating the Expression of Anpep via mmu_circRNA_22187
por: Yan, Li, et al.
Publicado: (2021)

Chondroprotective Mechanism of Eucommia ulmoides Oliv.-Glycyrrhiza uralensis Fisch. Couplet Medicines in Knee Osteoarthritis via Experimental Study and Network Pharmacology Analysis
por: Wang, Pinger, et al.
Publicado: (2023)

Prognosis after autologous peripheral blood stem cell transplantation for osteonecrosis of the femoral head in the pre-collapse stage: a retrospective cohort study
por: Pan, Jiafei, et al.
Publicado: (2020)

Shen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro
por: Qin, Gaofeng, et al.
Publicado: (2021)

An Shen Ding Zhi Ling Ameliorates the Symptoms of Attention Deficit Hyperactivity Disorder via Modulating Brain-Derived Neurotrophic Factor-Related Signaling Pathways
por: Yaqun, Li, et al.
Publicado: (2022)

Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway
por: Zhang, Zepeng, et al.
Publicado: (2020)

A randomized, double-blind, placebo-controlled trial for Yi-Qi Hua-Yu tong-sui granule in the treatment of mild or moderate cervical spondylotic myelopathy
por: Xu, Chongqing, et al.
Publicado: (2020)

Effect of the herbal formulation Shen-Zhi-Ling on an APP/PS1 mouse model of Alzheimer's disease by modulating the biliverdin reductase/heme oxygenase 1 system
por: Xing, Sanli, et al.
Publicado: (2017)

Correction to: Shen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro
por: Qin, Gaofeng, et al.
Publicado: (2021)

Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats
por: Lin, Shiuan-Pey, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_04c6rraslghs4paoicsbhvc6ml