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TFEB insufficiency promotes cardiac hypertrophy by blocking autophagic degradation of GATA4

Autophagosome–lysosome pathway (ALP) insufficiency has been suggested to play a critical role in the pathogenesis of cardiac hypertrophy. However, the mechanisms underlying ALP insufficiency remain largely unknown, and strategies to specifically manipulate ALP insufficiency for treating cardiac hype...

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Detalles Bibliográficos
Autores principales:	Song, Rui, Lei, Han, Feng, Li, Cheng, Wanwen, Li, Ying, Yao, Ling Ling, Liu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498468/ https://www.ncbi.nlm.nih.gov/pubmed/34517007 http://dx.doi.org/10.1016/j.jbc.2021.101189

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